Research
A Case of Recalcitrant Warts Cured with Combination Therapy
December 1, 2025
This case describes a 61-year-old man with a 15-year history of a large plantar mosaic wart on his right foot that had not responded to liquid nitrogen, salicylic acid, electrodesiccation and curettage, or Candida antigen injections.
He was treated with the SWIFT® microwave device, at each session the lesion was pared to aid energy penetration, then five two-second pulses were delivered to multiple quadrants of the wart, with each appointment taking 5–10 minutes. After five sessions over nine months the wart resolved completely, with no scarring or pigment change. Treatment was well tolerated, with no blistering, scabbing or downtime, which suited the patient’s active lifestyle as a runner and golfer. The author concludes that combining immunomodulation with cytotoxic therapy can resolve treatment-resistant warts, while noting HPV’s potential to recur.